Pharmacogenomics is the study of how genes affect a person’s response to drugs. This science has given rise to the practice of “precision medicine,” which combines pharmacology (the study of medication) and genomics (the study of genes and their functions) to help prescribers make more personalized medication choices. These include which medications to prescribe to different individuals and what doses will have the best effects. This presentation integrates concepts of neurobiology and neuropathology with genetics and genomics to produce new models for diagnosis and personalized treatment for depressive disorders. The results of the GUIDED study are presented to highlight the efficacy of this approach. | 1.50 credits (1.25 Pharmacology) | $40

Updated diagnostic criteria and disease models for anxiety disorders are reviewed. Neurobiological and epigenetic mechanisms that underlie anxiety symptoms are presented as the basis for therapeutic interventions. Specific attention is given to the formulation of rational, genomically-informed pharmacologic treatment approaches for anxiety disorders. Practical applications for nurse practitioners are presented. | 1.5 credits (1.25 Pharmacology) | $40